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Percentage of viable protoscolices after exposure to different doses of <t>fluralaner</t> at 1 h, 6 h and 24 h time interval
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Percentage of viable protoscolices after exposure to different doses of <t>fluralaner</t> at 1 h, 6 h and 24 h time interval
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Percentage of viable protoscolices after exposure to different doses of <t>fluralaner</t> at 1 h, 6 h and 24 h time interval
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Percentage of viable protoscolices after exposure to different doses of <t>fluralaner</t> at 1 h, 6 h and 24 h time interval
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Percentage of viable protoscolices after exposure to different doses of <t>fluralaner</t> at 1 h, 6 h and 24 h time interval
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Percentage of viable protoscolices after exposure to different doses of <t>fluralaner</t> at 1 h, 6 h and 24 h time interval
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Percentage of viable protoscolices after exposure to different doses of <t>fluralaner</t> at 1 h, 6 h and 24 h time interval
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Image Search Results


Percentage of viable protoscolices after exposure to different doses of fluralaner at 1 h, 6 h and 24 h time interval

Journal: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology

Article Title: Study on the effect of an ion channel inhibitor “Fluralaner” on Echinococcus granulosus protoscolices and metacestode layers in vitro

doi: 10.1007/s12639-020-01224-6

Figure Lengend Snippet: Percentage of viable protoscolices after exposure to different doses of fluralaner at 1 h, 6 h and 24 h time interval

Article Snippet: A fluralaner pack size of 25 mg was purchased from TargetMol (Cat. No. T5330).

Techniques:

Morphological alterations of E. granulosus protoscolices after 1 h incubation with different doses of fluralaner, stained with H & E. a–c Examples of control PSCs; showed normal intact PSCs, with visible hooks and calcareous corpuscles (Cr). d–f Treated PSCs with 12.5 ug/ml; showed vacuoles formation, multiple deformities (arrow). G-I: Treated PSCs with 100 ug/ml; showed detachment of cuticle (de) and complete loss of integrity (loss of hooks, scolex, and suction cup) (× 400)

Journal: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology

Article Title: Study on the effect of an ion channel inhibitor “Fluralaner” on Echinococcus granulosus protoscolices and metacestode layers in vitro

doi: 10.1007/s12639-020-01224-6

Figure Lengend Snippet: Morphological alterations of E. granulosus protoscolices after 1 h incubation with different doses of fluralaner, stained with H & E. a–c Examples of control PSCs; showed normal intact PSCs, with visible hooks and calcareous corpuscles (Cr). d–f Treated PSCs with 12.5 ug/ml; showed vacuoles formation, multiple deformities (arrow). G-I: Treated PSCs with 100 ug/ml; showed detachment of cuticle (de) and complete loss of integrity (loss of hooks, scolex, and suction cup) (× 400)

Article Snippet: A fluralaner pack size of 25 mg was purchased from TargetMol (Cat. No. T5330).

Techniques: Incubation, Staining

TEM of E. granulosus protoscolices after 1-h incubation with different doses of fluralaner compared to control protoscolices. Figure a-c Control protoscolices showing the distinct features of the protoscolices such as; Germinal layer (GL) that contain numerous cell types, Tegumental Layer (Teg), projection of intact microtriches (Mt) (arrows) into Laminated layer (LL). Figure d–f Treated protoscolices showing morphological changes as sheading of microtriches (arrows), the occurrence of lipid droplets (Ld) and vacuolation (Vac). A (x7500), B&C (x4000), D (x3000), E (x2000), F (x5000)

Journal: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology

Article Title: Study on the effect of an ion channel inhibitor “Fluralaner” on Echinococcus granulosus protoscolices and metacestode layers in vitro

doi: 10.1007/s12639-020-01224-6

Figure Lengend Snippet: TEM of E. granulosus protoscolices after 1-h incubation with different doses of fluralaner compared to control protoscolices. Figure a-c Control protoscolices showing the distinct features of the protoscolices such as; Germinal layer (GL) that contain numerous cell types, Tegumental Layer (Teg), projection of intact microtriches (Mt) (arrows) into Laminated layer (LL). Figure d–f Treated protoscolices showing morphological changes as sheading of microtriches (arrows), the occurrence of lipid droplets (Ld) and vacuolation (Vac). A (x7500), B&C (x4000), D (x3000), E (x2000), F (x5000)

Article Snippet: A fluralaner pack size of 25 mg was purchased from TargetMol (Cat. No. T5330).

Techniques: Incubation

TEM in E.granulosus camel metacestode layers after 1-h incubation with different doses of fluralaner compared to control. a Control sample showing intact germinal layer and the characteristic multicellular structure. b, c treated metacestode showing detachment of germinal layer with only cellular debris remaining and the detachment of tegument (arrow) from the laminated layer (LL). d, e: treated metacestode showing complete disappearance of the germinal layer and some destruction in the laminated layer (arrow). A (x7500), B (x4000), C (x3000), D&E (x1500)

Journal: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology

Article Title: Study on the effect of an ion channel inhibitor “Fluralaner” on Echinococcus granulosus protoscolices and metacestode layers in vitro

doi: 10.1007/s12639-020-01224-6

Figure Lengend Snippet: TEM in E.granulosus camel metacestode layers after 1-h incubation with different doses of fluralaner compared to control. a Control sample showing intact germinal layer and the characteristic multicellular structure. b, c treated metacestode showing detachment of germinal layer with only cellular debris remaining and the detachment of tegument (arrow) from the laminated layer (LL). d, e: treated metacestode showing complete disappearance of the germinal layer and some destruction in the laminated layer (arrow). A (x7500), B (x4000), C (x3000), D&E (x1500)

Article Snippet: A fluralaner pack size of 25 mg was purchased from TargetMol (Cat. No. T5330).

Techniques: Incubation